Michelanglo — VENUS

Assessing the effect of amino acid variants have on structure

A tool to help in the discovery of why a given mutation is pathogenic (see documentation). To view multiple mutations at the same time see multiple mutant page. For a random protein and mutation click here. For an ENSEMBL id click here.

Unrecognised name
Gene/prot. name
Unrecognised name
AA mutation
Unrecognised mutation
Advanced options

In most cases it is not necessary to alter these settings. For description see documentation.

Cutoff for SwissModel identity (oligomer)    40
Cutoff for SwissModel identity (monomer)    70
Cutoff for SwissModel quality (qMean) (oligomer)    -2
Cutoff for SwissModel quality (qMean) (monomer)    -2
FastRelax cycles    2
FastRelax C-beta neighbourhood radius    12